Title : The transfection-induced overexpression of IGF-binding protein-4 affects the secretory activity of porcine ovarian granulosa cells and their response to hormones and IGF-I.

Pub. Date : 2001 Jun

PMID : 11357060






2 Functional Relationships(s)
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1 It was observed that GH, IGF-I, estradiol, LH and oxytocin alter the progesterone, oxytocin, IGF-I and IGFBP-3 release by porcine ovarian granulosa cells. Progesterone oxytocin/neurophysin I prepropeptide Homo sapiens
2 The present results suggested that IGFBP-4, as well as GH, IGF-I, estradiol, LH and oxytocin, is a potent regulator of porcine ovarian steroid (progesterone), nonapeptide hormone (oxytocin), growth factor (IGF-I) and growth factor-binding protein (IGFBP-3) release. Progesterone oxytocin/neurophysin I prepropeptide Homo sapiens