Title : Insulin-induced c-Jun N-terminal kinase activation is negatively regulated by protein kinase C delta.

Pub. Date : 2001 Jun

PMID : 11356718






2 Functional Relationships(s)
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1 Insulin-induced JNK activation was potentiated by either preincubating cells with 2 nM GF109203X (PKC inhibitor) or down-regulation of PKC by overnight treatment with 100 nM tetradecanoyl phorbol acetate. Tetradecanoylphorbol Acetate insulin Homo sapiens
2 In contrast, brief preincubation with 100 nM tetradecanoyl phorbol acetate inhibited the insulin- induced JNK activation. Tetradecanoylphorbol Acetate insulin Homo sapiens