Title : Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor.

Pub. Date : 2001 Jun

PMID : 11353749






1 Functional Relationships(s)
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1 Moreover, etoricoxib (0.1-100 microM) was found to be a relatively weak inhibitor (IC(50) > 100 microM) of multiple P450s (CYP1A2, CYP2D6, CYP3A, CYP2E1, CYP2C9, and CYP2C19) in human liver microsomes. Etoricoxib cytochrome P450 family 2 subfamily D member 6 Homo sapiens