Title : Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor.

Pub. Date : 2001 Jun

PMID : 11353749






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor. Etoricoxib prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Etoricoxib, a potent and selective cyclooxygenase-2 inhibitor, was shown to be metabolized via 6"-methylhydroxylation (M2 formation) when incubated with NADPH-fortified human liver microsomes. Etoricoxib prostaglandin-endoperoxide synthase 2 Homo sapiens