Title : Chemokine receptor homo- or heterodimerization activates distinct signaling pathways.

Pub. Date : 2001 May 15

PMID : 11350939






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This has functional consequences, as the CCR2 and CCR5 ligands monocyte chemotactic protein-1 (MCP-1) and RANTES (regulated upon activation, normal T cell-expressed and secreted) cooperate to trigger calcium responses at concentrations 10- to 100-fold lower than the threshold for either chemokine alone. Calcium C-C motif chemokine ligand 2 Homo sapiens
2 This has functional consequences, as the CCR2 and CCR5 ligands monocyte chemotactic protein-1 (MCP-1) and RANTES (regulated upon activation, normal T cell-expressed and secreted) cooperate to trigger calcium responses at concentrations 10- to 100-fold lower than the threshold for either chemokine alone. Calcium C-C motif chemokine ligand 2 Homo sapiens