Title : The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

Pub. Date : 2001 May

PMID : 11343253






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens
2 For decades, phenobarbital (PB) treatment for hyperbilirubinemia has been known to increase expression of the UGT1A1 gene in liver. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens
3 For decades, phenobarbital (PB) treatment for hyperbilirubinemia has been known to increase expression of the UGT1A1 gene in liver. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens
4 We have now delineated the PB response activity to a 290-bp distal enhancer sequence (-3483/-3194) of the UGT1A1 gene. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens