Pub. Date : 2001 Apr 27
PMID : 11334889
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The presence of CuZn-SOD, Mn-SOD or Mn(II) enhanced the frequency of DNA damage induced by hydrogen peroxide (H2O2) and Cu(II), and altered the site specificity of the latter: H2O2 induced Cu(II)-dependent DNA damage with high frequency at the 5"-guanine of poly G sequences; when SODs were added, the frequency of cleavages at thymine and cytosine residues increased. | Hydrogen Peroxide | superoxide dismutase 2 | Homo sapiens |
| 2 | The presence of CuZn-SOD, Mn-SOD or Mn(II) enhanced the frequency of DNA damage induced by hydrogen peroxide (H2O2) and Cu(II), and altered the site specificity of the latter: H2O2 induced Cu(II)-dependent DNA damage with high frequency at the 5"-guanine of poly G sequences; when SODs were added, the frequency of cleavages at thymine and cytosine residues increased. | Hydrogen Peroxide | superoxide dismutase 2 | Homo sapiens |
| 3 | The presence of CuZn-SOD, Mn-SOD or Mn(II) enhanced the frequency of DNA damage induced by hydrogen peroxide (H2O2) and Cu(II), and altered the site specificity of the latter: H2O2 induced Cu(II)-dependent DNA damage with high frequency at the 5"-guanine of poly G sequences; when SODs were added, the frequency of cleavages at thymine and cytosine residues increased. | Hydrogen Peroxide | superoxide dismutase 2 | Homo sapiens |