Title : Inhibition of the expression of inducible nitric oxide synthase and cyclooxygenase-2 in macrophages by 7HQ derivatives: involvement of IkappaB-alpha stabilization.

Pub. Date : 2001 Apr 20

PMID : 11334875






1 Functional Relationships(s)
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1 Lipopolysaccharide, the active component of endotoxin, significantly induced the expression of inducible nitric oxide synthase and cyclooxygenase-2, leading to the accumulation of nitrite and prostaglandin E(2), respectively. Dinoprostone prostaglandin-endoperoxide synthase 2 Mus musculus