Title : Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.

Pub. Date : 2001 Apr 27

PMID : 11326099






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 tBID, the caspase-activated form of a "BH3-domain-only" BCL-2 family member, triggers the homooligomerization of "multidomain" conserved proapoptotic family members BAK or BAX, resulting in the release of cytochrome c from mitochondria. tBID BCL2 apoptosis regulator Homo sapiens