Pub. Date : 2001 Jan 25
PMID : 11313973
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | By prolonged nocodazole treatment, U251MG human glioma cell, which has a p53 mutation, underwent transient arrest at mitosis, and subsequently exited from mitotic arrest (termed "mitotic slippage") followed by DNA replication without cytokinesis, resulting in hyperploid formation. | Nocodazole | tumor protein p53 | Homo sapiens |
2 | By employing LN382 glioma cell that has a temperature-sensitive p53 mutation, we found that the activation of p53 prevents hyperploid formation after the prolonged nocodazole treatment. | Nocodazole | tumor protein p53 | Homo sapiens |
3 | By employing LN382 glioma cell that has a temperature-sensitive p53 mutation, we found that the activation of p53 prevents hyperploid formation after the prolonged nocodazole treatment. | Nocodazole | tumor protein p53 | Homo sapiens |