Pub. Date : 2001 Mar 15
PMID : 11313880
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p53 activation was followed by the formation of reactive oxygen species (ROS), superoxide anion (O2-*) measured by hydroethidium oxidation into ethidium and hydrogen peroxide (H2O2) measured by oxidation of 2",7"-dichlorofluorescin (DCFH) into 2",7"-dichlorofluorescein (DCF), which was accompanied with ceramide generation through the activation of neutral, but not acid, sphingomyelinase. | Hydrogen Peroxide | tumor protein p53 | Homo sapiens |
| 2 | p53 activation was followed by the formation of reactive oxygen species (ROS), superoxide anion (O2-*) measured by hydroethidium oxidation into ethidium and hydrogen peroxide (H2O2) measured by oxidation of 2",7"-dichlorofluorescin (DCFH) into 2",7"-dichlorofluorescein (DCF), which was accompanied with ceramide generation through the activation of neutral, but not acid, sphingomyelinase. | Hydrogen Peroxide | tumor protein p53 | Homo sapiens |