Title : Alkyl-lysophospholipid 1-O-octadecyl-2-O-methyl- glycerophosphocholine induces invasion through episialin-mediated neutralization of E-cadherin in human mammary MCF-7 cells in vitro.

Pub. Date : 2001 May 15

PMID : 11304687






3 Functional Relationships(s)
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1 In the present study, we tested the effect of ET-18-OMe on adhesion, invasion and localisation of episialin and E-cadherin in MCF-7/AZ cells expressing a functional E-cadherin/catenin complex. edelfosine mucin 1, cell surface associated Homo sapiens
2 ET-18-OMe induced finger-like extensions with clustering of episialin together with E-cadherin and carcinoembryonic antigen but not with occludin. edelfosine mucin 1, cell surface associated Homo sapiens
3 In cells in suspension, ET-18-OMe caused a shift in the flow-cytometric profile of episialin toward a lower intensity for MCF-7/AZ cells. edelfosine mucin 1, cell surface associated Homo sapiens