Title : Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells.

Pub. Date : 2001 Apr

PMID : 11304462






1 Functional Relationships(s)
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1 Pretreatment of vascular smooth muscle cells with the antioxidants diphenylene iodonium, Tiron, N-acetylcysteine, and ebselen significantly inhibited ( approximately 80% to 90%) tyrosine phosphorylation of the EGF-R by Ang II but not by EGF. diphenyleneiodonium angiotensinogen Homo sapiens