Title : Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats.

Pub. Date : 2001 Mar

PMID : 11303587






1 Functional Relationships(s)
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1 Importantly, DFMO-treated ZD esophagi display increased rate of apoptosis accompanied by intense bax expression and greatly reduced cell proliferation by proliferating cell nuclear antigen expression. Eflornithine BCL2 associated X, apoptosis regulator Rattus norvegicus