Title : Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.

Pub. Date : 2001 Apr 6

PMID : 11301059






1 Functional Relationships(s)
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1 In whole-cell patch clamp studies, capsaicin (10 microM) elicited a slowly activating/deactivating inward current in human embryonic kidney (HEK293) cells stably expressing human vanilloid VR1 receptor, which exhibited pronounced outward rectification (reversal potential -2.1+/-0.2 mV) and was abolished by capsazepine (10 microM). Capsaicin transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus