Pub. Date : 2001 Mar 27
PMID : 11297432
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the current studies, we show that hypochlorous acid (HOCl), generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes, cross-links single-stranded DNA-binding protein (SSB) to single-stranded oligonucleotides. | Chlorides | myeloperoxidase | Homo sapiens |
| 2 | The covalent complex of radiolabeled dT(40) and SSB was also generated by chloramines and the complete myeloperoxidase-hydrogen peroxide-chloride system. | Chlorides | myeloperoxidase | Homo sapiens |
| 3 | The enzymatic reaction required each component of the system and was inhibited by heme poisons and chloride-free conditions, implicating myeloperoxidase and HOCl. | Chlorides | myeloperoxidase | Homo sapiens |