Title : Depletion of acyl-coenzyme A-binding protein affects sphingolipid synthesis and causes vesicle accumulation and membrane defects in Saccharomyces cerevisiae.

Pub. Date : 2001 Apr

PMID : 11294913






2 Functional Relationships(s)
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1 A conditional knockout strain (Y700pGAL1-ACB1) with the ACB1 gene under control of the GAL1 promoter exhibited an altered acyl-CoA profile with a threefold increase in the relative content of C18:0-CoA, without affecting total acyl-CoA level as previously reported for an adapted acb1Delta strain. Acyl Coenzyme A long-chain fatty acid transporter ACB1 Saccharomyces cerevisiae S288C
2 A conditional knockout strain (Y700pGAL1-ACB1) with the ACB1 gene under control of the GAL1 promoter exhibited an altered acyl-CoA profile with a threefold increase in the relative content of C18:0-CoA, without affecting total acyl-CoA level as previously reported for an adapted acb1Delta strain. Acyl Coenzyme A long-chain fatty acid transporter ACB1 Saccharomyces cerevisiae S288C