Title : Isolated rat stomach ECL cells generate prostaglandin E(2) in response to interleukin-1 beta, tumor necrosis factor-alpha and bradykinin.

Pub. Date : 2001 Mar 30

PMID : 11290377






3 Functional Relationships(s)
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1 Gastrin and pituitary adenylate cyclase-activating peptide (PACAP) stimulate histamine secretion from isolated ECL cells, while somatostatin and galanin inhibit stimulated secretion. Histamine gastrin Rattus norvegicus
2 Incubating ECL cells in the presence of interleukin-1 beta+bradykinin for 24 h reduced their ability to secrete histamine in response to gastrin. Histamine gastrin Rattus norvegicus
3 Also, increasing the concentrations of hydrocortisone in the medium resulted in an enhanced gastrin-stimulated histamine secretion. Histamine gastrin Rattus norvegicus