Title : A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

Pub. Date : 2001 Apr 10

PMID : 11287630






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 mTOR induced the serine phosphorylation of IRS-1 (Ser-636/639), and such phosphorylation was inhibited by rapamycin. Sirolimus insulin receptor substrate 1 Homo sapiens