Title : Neuropeptide Y Y2 receptor signalling mechanisms in the human glioblastoma cell line LN319.

Pub. Date : 2001 Mar

PMID : 11287092






2 Functional Relationships(s)
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1 We have recently characterized a human glioblastoma cell line, LN319, that expresses exclusively NPY Y2 receptors and have demonstrated that NPY triggers transient decreases in cAMP and increases in intracellular calcium responses. Cyclic AMP neuropeptide Y Homo sapiens
2 Part of the response was sensitive to pertussis toxin (PTX) under conditions where the toxin totally abolished the NPY-mediated effects on cAMP. Cyclic AMP neuropeptide Y Homo sapiens