Pub. Date : 2001 Apr
PMID : 11287034
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aspirin dose dependently inhibits the interleukin-1 beta-stimulated increase in inducible nitric oxide synthase, nitric oxide, and prostaglandin E(2) production in rat ovarian dispersates cultured in vitro. | Aspirin | nitric oxide synthase 2 | Rattus norvegicus |
| 2 | OBJECTIVE: Determine if aspirin inhibits the IL-1 beta-stimulated expression of inducible nitric oxide synthase (iNOS), nitric oxide (NO), and prostaglandin E(2) (PGE(2)) in rat ovarian dispersates cultured in vitro. | Aspirin | nitric oxide synthase 2 | Rattus norvegicus |
| 3 | OBJECTIVE: Determine if aspirin inhibits the IL-1 beta-stimulated expression of inducible nitric oxide synthase (iNOS), nitric oxide (NO), and prostaglandin E(2) (PGE(2)) in rat ovarian dispersates cultured in vitro. | Aspirin | nitric oxide synthase 2 | Rattus norvegicus |
| 4 | Coadministration of IL-1 beta and aspirin (10 mM) attenuates IL-1 beta-stimulated iNOS expression after culture for 24 and 48 hours. | Aspirin | nitric oxide synthase 2 | Rattus norvegicus |
| 5 | CONCLUSION(S): Aspirin significantly inhibits the IL-1 beta-stimulated expression of iNOS, NO, and PGE(2) in ovarian dispersates cultured in vitro. | Aspirin | nitric oxide synthase 2 | Rattus norvegicus |