Title : Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562.

Pub. Date : 2001 Apr 6

PMID : 11286477






2 Functional Relationships(s)
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1 In parallel, the expression of functional P-glycoprotein was delayed after concomitant addition of dexrazoxane to the selecting medium (P< 0.001). Dexrazoxane ATP binding cassette subfamily B member 1 Homo sapiens
2 These results suggest that dexrazoxane may delay the development of MDR1, thus allowing responders to the FAC regime to continue to respond. Dexrazoxane ATP binding cassette subfamily B member 1 Homo sapiens