Title : Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein.

Pub. Date : 2001 Apr 10

PMID : 11284689






1 Functional Relationships(s)
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Protein Name
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1 MDR1 cDNA with the G185V substitution was used in a function-based selection to identify mutations that would further increase Pgp-mediated resistance to etoposide. Etoposide ATP binding cassette subfamily B member 1 Homo sapiens