Title : The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase.

Pub. Date : 2001 Jun 15

PMID : 11283006






1 Functional Relationships(s)
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1 We suggest that activation of the pyrimidine ring via covalent addition at C-6 is a major contributor to the rate of the chemistry step (k(chem)) in the case of cytosine but not 5-fluorocytosine. pyrimidine complement C6 Homo sapiens