Title : Mechanisms of interleukin 1beta-induced human airway smooth muscle hyporesponsiveness to histamine. Involvement of p38 MAPK NF-kappaB.

Pub. Date : 2001 Mar

PMID : 11282781






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mechanisms of interleukin 1beta-induced human airway smooth muscle hyporesponsiveness to histamine. Histamine interleukin 1 beta Homo sapiens
2 We have investigated the effect of IL-1beta on histamine H(1)-receptor (H(1)R)-mediated inositol phosphate (IP) accumulation in human airway smooth muscle cells (HASMC) and on histamine-induced contraction of human bronchial rings. Histamine interleukin 1 beta Homo sapiens
3 Stimulation of HASMC for 24 h with IL-1beta resulted in significant loss of histamine-induced IP formation, which was associated with a reduction of histamine- induced contraction of IL-1beta-treated human bronchial rings. Histamine interleukin 1 beta Homo sapiens
4 Stimulation of HASMC for 24 h with IL-1beta resulted in significant loss of histamine-induced IP formation, which was associated with a reduction of histamine- induced contraction of IL-1beta-treated human bronchial rings. Histamine interleukin 1 beta Homo sapiens
5 Stimulation of HASMC for 24 h with IL-1beta resulted in significant loss of histamine-induced IP formation, which was associated with a reduction of histamine- induced contraction of IL-1beta-treated human bronchial rings. Histamine interleukin 1 beta Homo sapiens