Pub. Date : 2000 Sep
PMID : 11281730
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This and UO126, another MEK inhibitor were ably to reproducibly inhibit p45-JNK activation induced by hydrogen peroxide. | U 0126 | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | It is concluded that JNK mediates H(2)O(2)-induced cellular injury in the HT29 cell line, and additionally, we report for the first time that JNK activation can be inhibited by both PD98059 and UO126 at conventional doses used to inhibit MEK. | U 0126 | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | It is concluded that JNK mediates H(2)O(2)-induced cellular injury in the HT29 cell line, and additionally, we report for the first time that JNK activation can be inhibited by both PD98059 and UO126 at conventional doses used to inhibit MEK. | U 0126 | mitogen-activated protein kinase 8 | Homo sapiens |