Pub. Date : 2001 May 11
PMID : 11278982
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 2 | Activation of JNK by H(2)O(2) was also inhibited by AG1478 and antisense oligonucleotides directed against the epidermal growth factor receptor (EGFR), implicating the EGFR in this process. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 3 | Activation of JNK by H(2)O(2) was also inhibited by AG1478 and antisense oligonucleotides directed against the epidermal growth factor receptor (EGFR), implicating the EGFR in this process. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 4 | Activation of JNK by H(2)O(2) was also inhibited by AG1478 and antisense oligonucleotides directed against the epidermal growth factor receptor (EGFR), implicating the EGFR in this process. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 5 | Consistent with this observation, H(2)O(2) stimulated EGFR tyrosine phosphorylation and complex formation with Shc-Grb2 that was abolished by PP2, implicating Src in H(2)O(2)-induced EGFR activation. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 6 | Consistent with this observation, H(2)O(2) stimulated EGFR tyrosine phosphorylation and complex formation with Shc-Grb2 that was abolished by PP2, implicating Src in H(2)O(2)-induced EGFR activation. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 7 | Consistent with this observation, H(2)O(2) stimulated EGFR tyrosine phosphorylation and complex formation with Shc-Grb2 that was abolished by PP2, implicating Src in H(2)O(2)-induced EGFR activation. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |
| 8 | These data indicate that H(2)O(2)-induced JNK activation in endothelial cells involves the EGFR through an Src-dependent pathway that is distinct from EGFR ligand activation. | Hydrogen Peroxide | epidermal growth factor receptor | Homo sapiens |