Title : Atp-bound topoisomerase ii as a target for antitumor drugs.

Pub. Date : 2001 May 11

PMID : 11278845






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Second, C427A mutant human TOP2alpha, which exhibits reduced ATPase activity, was shown to exhibit cross-resistance to all ATP-sensitive but not ATP-insensitive TOP2 poisons. Adenosine Triphosphate DNA topoisomerase II alpha Homo sapiens
2 Second, C427A mutant human TOP2alpha, which exhibits reduced ATPase activity, was shown to exhibit cross-resistance to all ATP-sensitive but not ATP-insensitive TOP2 poisons. Adenosine Triphosphate DNA topoisomerase II alpha Homo sapiens