Title : Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells.

Pub. Date : 2001 Apr 13

PMID : 11278407






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 S1P treatment of BAEC leads to eNOS phosphorylation at Ser(1179), a residue phosphorylated by Akt; an eNOS mutant in which this Akt phosphorylation site is inactivated shows attenuated S1P-induced eNOS activation. Serine nitric oxide synthase 3 Bos taurus