Pub. Date : 1994
PMID : 11271305
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effect of immunosuppressive agents FK 506 and cyclosporin and steroids on the expression of IL-6 and its receptor by stimulated lymphocytes and monocytes. | Tacrolimus | interleukin 6 | Homo sapiens |
2 | Dexamethazone, cyclosporin (CyA), and FK 506 at immunosuppressive concentrations induced a dose-dependent inhibition of IL-6 secretion from adherent monocytes (MO) stimulated with phytohemagglutinin (PHA). | Tacrolimus | interleukin 6 | Homo sapiens |
3 | FK 506, CyA, and steroids may exert their immunosuppressive effect by inhibiting IL-6 secretion and partially restoring MO IL-6R, which may be important in protecting the cell target against IL-6 autocrine stimulation. | Tacrolimus | interleukin 6 | Homo sapiens |
4 | FK 506, CyA, and steroids may exert their immunosuppressive effect by inhibiting IL-6 secretion and partially restoring MO IL-6R, which may be important in protecting the cell target against IL-6 autocrine stimulation. | Tacrolimus | interleukin 6 | Homo sapiens |