Title : 2-Bromoethylamine as a potent selective suicide inhibitor for semicarbazide-sensitive amine oxidase.

Pub. Date : 2001 Mar 15

PMID : 11266660






4 Functional Relationships(s)
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1 Semicarbazide-sensitive amine oxidase (SSAO) catalyzes the deamination of methylamine and aminoacetone to produce toxic aldehydes, i.e. formaldehyde and methylglyoxal, as well as hydrogen peroxide and ammonia. Aldehydes amine oxidase copper containing 2 Homo sapiens
2 Semicarbazide-sensitive amine oxidase (SSAO) catalyzes the deamination of methylamine and aminoacetone to produce toxic aldehydes, i.e. formaldehyde and methylglyoxal, as well as hydrogen peroxide and ammonia. Aldehydes amine oxidase copper containing 2 Homo sapiens
3 The aldehyde trapping agent o-phenylenediamine was capable of preventing 2-BrEA-induced inhibition of SSAO activity. Aldehydes amine oxidase copper containing 2 Homo sapiens
4 An aldehyde product was detected to be an initial product of 2-BrEA after it was incubated with SSAO. Aldehydes amine oxidase copper containing 2 Homo sapiens