Title : Where is the evidence that cyclooxygenase inhibition is the primary cause of nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal injury? Topical injury revisited.

Pub. Date : 2001 Mar 15

PMID : 11266647






1 Functional Relationships(s)
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1 Indeed, development of the new "super aspirins," such as Celebrex and Vioxx, that selectively inhibit the inducible COX-2, expressed in areas of inflammation, is a direct outgrowth of this concept. Aspirin mitochondrially encoded cytochrome c oxidase II Homo sapiens