Pub. Date : 2001
PMID : 11261750
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CSF-folate levels are decreased in late-onset AD patients. | Folic Acid | colony stimulating factor 2 | Homo sapiens |
| 2 | Remarkably CSF-folate levels are 3 to 4 times higher than blood-folate levels. | Folic Acid | colony stimulating factor 2 | Homo sapiens |
| 3 | To reach the brain, folates are actively transported by choroid plexus (CP) as well as vitamins B6, B12, C and E. Epithelial atrophy having been reported in aging and in Alzheimer"s disease (AD), we measured the CSF folate-levels of 126 patients, including 30 AD consecutive patients to evaluate whether CP functions of folate-transport were impaired. | Folic Acid | colony stimulating factor 2 | Homo sapiens |
| 4 | To reach the brain, folates are actively transported by choroid plexus (CP) as well as vitamins B6, B12, C and E. Epithelial atrophy having been reported in aging and in Alzheimer"s disease (AD), we measured the CSF folate-levels of 126 patients, including 30 AD consecutive patients to evaluate whether CP functions of folate-transport were impaired. | Folic Acid | colony stimulating factor 2 | Homo sapiens |
| 5 | CSF-folate concentrations did not vary with age (10.47 +/- 1.93ng/ml between 20 and 60 years; 9.96 +/- 2.01 ng/ml in elderly control patients older than 60 years of age, p > 0.05) while late-onset AD patients had significantly lower CSF-folate levels (8.26 +/- 1.82 ng/ml, p < 0.001). | Folic Acid | colony stimulating factor 2 | Homo sapiens |