Title : Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue.

Pub. Date : 2001 May 25

PMID : 11259409






9 Functional Relationships(s)
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1 Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
2 Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
3 Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
4 Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
5 Using this approach, we altered the ATP-binding site on JNK and identified N(6)-(2-phenythyl)-ATP, a modified form of ATP that exhibits high specificity and affinity for the modified, but not the wild type form, of JNK. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
6 Using this approach, we altered the ATP-binding site on JNK and identified N(6)-(2-phenythyl)-ATP, a modified form of ATP that exhibits high specificity and affinity for the modified, but not the wild type form, of JNK. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
7 Using this approach, we altered the ATP-binding site on JNK and identified N(6)-(2-phenythyl)-ATP, a modified form of ATP that exhibits high specificity and affinity for the modified, but not the wild type form, of JNK. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
8 Using modified JNK and its ATP analogue enables the detection of novel JNK substrates. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
9 Using modified JNK and its ATP analogue enables the detection of novel JNK substrates. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens