Title : U73122 inhibits the dephosphorylation and translocation of cofilin in activated macrophage-like U937 cells.

Pub. Date : 2001 Jan

PMID : 11257443






1 Functional Relationships(s)
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1 We found that 1-[6-[[17beta-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U73122), an inhibitor of phospholipase C (PLC), suppressed both opsonized zymosan (OZ)-induced dephosphorylation and translocation of cofilin in macrophage-like U937 cells at 4 microM concentration. Hydrogen cofilin 1 Homo sapiens