Title : Statin therapy and reductions in low-density lipoprotein cholesterol: initial clinical data on the potent new statin Rosuvastatin.

Pub. Date : 2001 Mar 8

PMID : 11256849






2 Functional Relationships(s)
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1 In dose-ranging studies of patients with hypercholesterolemia, the new synthetic statin rosuvastatin (formerly ZD4522) produced significant, dose-dependent reductions in LDL-C compared with placebo across a range of doses. Rosuvastatin Calcium component of oligomeric golgi complex 2 Homo sapiens
2 Reductions ranged from 34% at 1 mg per day to 65% at 80 mg per day, with linear regression analysis indicating an additional 4.5% reduction in LDL-C with each doubling of the rosuvastatin dose. Rosuvastatin Calcium component of oligomeric golgi complex 2 Homo sapiens