Title : Local factor production by MG63 osteoblast-like cells in response to surface roughness and 1,25-(OH)2D3 is mediated via protein kinase C- and protein kinase A-dependent pathways.

Pub. Date : 2001 Apr

PMID : 11246968






2 Functional Relationships(s)
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Protein Name
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1 MG63 cells exhibit decreased proliferation and increased differentiation when cultured on rough Ti surfaces (Ra > 2 microm) and response to 1,25-(OH)2D3 is enhanced, resulting in synergistic increases in TGF-beta1 and PGE2. Calcitriol transforming growth factor beta 1 Homo sapiens
2 The effect of 1,25-(OH)2D3 on TGF-beta1 production is not via PKC. Calcitriol transforming growth factor beta 1 Homo sapiens