Title : 9-cis-Retinoic acid represses transcription of the gonadotropin-releasing hormone (GnRH) gene via proximal promoter region that is distinct from all-trans-retinoic acid response element.

Pub. Date : 2001 Mar 5

PMID : 11245924






1 Functional Relationships(s)
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1 Transient transfections of serial deletion constructs of the rat GnRH promoter revealed that the --230/--110 sequence of the rat GnRH promoter is responsible for 9-cis-RA-induced inhibition of GnRH transcription. Radium gonadotropin releasing hormone 1 Rattus norvegicus