Title : [A study on the tumor suppressing effect of a specific point mutant p53 minigene in the expression regulated model with a tetracycline-transactivative response promoter].

Pub. Date : 1998 Oct

PMID : 11245004






1 Functional Relationships(s)
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1 OBJECTIVE: To establish a tetracycline-regulated expression model and to determine and verify whether a specific point mutant type p53 minigene, containing an Arg-->Leu substitution at amino acid 172, possesses a suppressing effect on human lung cancer. Leucine tumor protein p53 Homo sapiens