Pub. Date : 2001 Mar
PMID : 11243859
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The irritant action of capsaicin is mediated by the vanilloid receptor, VR1, which is expressed in sensory neurons termed nociceptors. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 2 | Capsaicin (EC(50) = 853 nM), low pH (<5.5), and noxious heat (44 degrees C) activate hVR1 expressed in Xenopus oocytes. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 3 | Subthreshold pH (6.4) sensitizes VR1 to capsaicin (EC(50) = 221 nM). | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |