Title : Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells.

Pub. Date : 2001 Mar

PMID : 11243424






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment with vitamin C for 24 h significantly increased levels of the eNOS co-factor tetrahydrobiopterin (BH4), whereas MnTBAP did not affect its levels. sapropterin nitric oxide synthase 3 Homo sapiens
2 Treatment with vitamin C for 24 h significantly increased levels of the eNOS co-factor tetrahydrobiopterin (BH4), whereas MnTBAP did not affect its levels. sapropterin nitric oxide synthase 3 Homo sapiens
3 Sepiapterin (10(-4) M), a precursor of BH4, significantly increased eNOS activity, whereas addition of vitamin C to cells treated with sepiapterin did not cause any further increase in eNOS activity. sapropterin nitric oxide synthase 3 Homo sapiens