Title : Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase.

Pub. Date : 2001 Mar

PMID : 11228164






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We show that epidermal growth factor (EGF) receptor activation, either directly by EGF or indirectly via the G-protein coupled receptor (GPCR) agonist lysophosphatidic acid (LPA), induces cleavage of Met through activation of the Erk MAP kinase signalling cascade. lysophosphatidic acid epidermal growth factor receptor Homo sapiens
2 We show that epidermal growth factor (EGF) receptor activation, either directly by EGF or indirectly via the G-protein coupled receptor (GPCR) agonist lysophosphatidic acid (LPA), induces cleavage of Met through activation of the Erk MAP kinase signalling cascade. lysophosphatidic acid epidermal growth factor receptor Homo sapiens