Title : Different behavioural profiles of the R(+)- and S(-)-enantiomers of 8-hydroxy-2-(di-n-propylamino) tetralin in the murine elevated plus-maze.

Pub. Date : 1996 Dec

PMID : 11224475






3 Functional Relationships(s)
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1 (=) 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) has been the most widely used pharmacological tool in research on 5-HT(1A) receptor function. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
2 (=) 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) has been the most widely used pharmacological tool in research on 5-HT(1A) receptor function. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
3 Findings are discussed in relation to differences in the intrinsic activity of 8-OH-DPAT isomers at 5-HT(1A) sites and the putative role of these receptors in anxiety-related processes. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus