Title : SH2 domain-mediated targeting, but not localization, of Syk in the plasma membrane is critical for FcepsilonRI signaling.

Pub. Date : 2001 Mar 1

PMID : 11222380






1 Functional Relationships(s)
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1 These findings suggest that SH2 domain-mediated membrane translocation of Syk is essential for the FcepsilonRI-mediated activation of Syk for downstream signaling events leading to histamine release. Histamine Fc epsilon receptor Ia Homo sapiens