Pub. Date : 2001 Jan
PMID : 11216854
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of P-glycoprotein mRNA transcripts by cycloheximide in animal tissues: evidence that class I Pgp is transcriptionally regulated whereas class II Pgp is post-transcriptionally regulated. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Induction of P-glycoprotein mRNA transcripts by cycloheximide in animal tissues: evidence that class I Pgp is transcriptionally regulated whereas class II Pgp is post-transcriptionally regulated. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | In this study, the protein synthesis inhibitor cycloheximide was used as a tool to understand Pgp gene expression and regulation in animal tissues. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | The results showed that cycloheximide significantly induced class II Pgp expression in all tissues examined. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | In contrast, the relatively modest increase in class I Pgp expression by cycloheximide was found to be mainly due to increased transcriptional activity. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | On the other hand, cycloheximide induced class III Pgp expression in some tissues while caused decay of class III Pgp mRNA in other tissues. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 7 | On the other hand, cycloheximide induced class III Pgp expression in some tissues while caused decay of class III Pgp mRNA in other tissues. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 8 | The transcriptional and post-transcriptional mechanisms exerted by cycloheximide on Pgp genes are discussed. | Cycloheximide | ATP binding cassette subfamily B member 1 | Homo sapiens |