Title : Transfer of the human NaI symporter gene enhances iodide uptake in hepatoma cells.

Pub. Date : 2001 Feb

PMID : 11216532






5 Functional Relationships(s)
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1 Transfer of the human NaI symporter gene enhances iodide uptake in hepatoma cells. Iodides solute carrier family 5 member 5 Homo sapiens
2 The transport of iodide across the cell membrane is mediated by the human NaI symporter (hNIS). Iodides solute carrier family 5 member 5 Homo sapiens
3 The transport of iodide across the cell membrane is mediated by the human NaI symporter (hNIS). Iodides solute carrier family 5 member 5 Homo sapiens
4 We therefore investigated whether the accumulation of iodide may be induced by the retroviral transfer of the hNIS gene in nonthyroid tumor cells. Iodides solute carrier family 5 member 5 Homo sapiens
5 In rats, the hNIS-expressing tumors accumulated six times more iodide than did the contralateral wild-type tumor as monitored by scintigraphy. Iodides solute carrier family 5 member 5 Homo sapiens