Pub. Date : 1975 Jan 28
PMID : 1120111
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | (1) The hydrophilic sulfate group directs the steroid molecule so that it only interacts with the active site of cytochrome P-450 with its non-sulfurylated, hydrophobic end. | Steroids | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | (2) The sulfate group interacts with the enzyme surface resulting in exposure of a slightly different part of the hydrophobic end of the substrate to the active site of cytochrome P-450 than when the same end of the free steroid is exposed to the active site of the enzyme. | Steroids | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |