Pub. Date : 2000
PMID : 11193883
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | VIP/PACAP binding to VPAC1 induces both a cAMP-dependent and a cAMP-independent pathways that regulate cytokine and NO production at the transcriptional level. | Cyclic AMP | adenylate cyclase activating polypeptide 1 | Mus musculus |
| 2 | VIP/PACAP binding to VPAC1 induces both a cAMP-dependent and a cAMP-independent pathways that regulate cytokine and NO production at the transcriptional level. | Cyclic AMP | adenylate cyclase activating polypeptide 1 | Mus musculus |
| 3 | Whereas the inhibition of IRF-1 and CRE-binding complexes seems to be mediated through the cAMP-dependent pathway, VIP/PACAP inhibition of NFkB nuclear translocation is mediated through a reduction in IkB alpha degradation mediated by the cAMP-independent pathway. | Cyclic AMP | adenylate cyclase activating polypeptide 1 | Mus musculus |