Title : Induction of CYP2C genes in human hepatocytes in primary culture.

Pub. Date : 2001 Mar

PMID : 11181490






2 Functional Relationships(s)
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1 The concentration dependence of CYP2C8 and CYP2C9 mRNAs in response to rifampicin and phenobarbital paralleled that of CYP3A4 and CYP2B6, the maximum accumulation being reached with 10 microM rifampicin and 100 microM phenobarbital. Phenobarbital cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 The concentration dependence of CYP2C8 and CYP2C9 mRNAs in response to rifampicin and phenobarbital paralleled that of CYP3A4 and CYP2B6, the maximum accumulation being reached with 10 microM rifampicin and 100 microM phenobarbital. Phenobarbital cytochrome P450 family 2 subfamily B member 6 Homo sapiens