Title : Solution structure of Grb2 reveals extensive flexibility necessary for target recognition.

Pub. Date : 2001 Feb 23

PMID : 11178911






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Binding experiments on Grb2 and peptides containing two different proline-rich sequences indicate that Grb2 adapts the relative position and orientation of the two SH3 domains to bind bivalently to the target peptide sequences. Proline growth factor receptor bound protein 2 Homo sapiens
2 Binding experiments on Grb2 and peptides containing two different proline-rich sequences indicate that Grb2 adapts the relative position and orientation of the two SH3 domains to bind bivalently to the target peptide sequences. Proline growth factor receptor bound protein 2 Homo sapiens